[ { "assertion": 1, "retraction": 0, "graph": "graph", "subject": "DOID:13372", "predicate": "IAO:0000115", "object": "A plasma protein metabolism disease that has_material_basis_in defective production of the protease inhibitor alpha 1-antitrypsin (A1AT), leading to decreased A1AT activity in the blood and lungs, and deposition of excessive abnormal A1AT protein in liver cells.", "datatype": "xsd:string", "annotation": "{\"dce:type\":[{\"datatype\":\"_IRI\",\"meta\":\"owl:Axiom\",\"object\":\"obo:ECO_0007638\"},{\"datatype\":\"_IRI\",\"meta\":\"owl:Axiom\",\"object\":\"obo:ECO_0007640\"}],\"oio:hasDbXref\":[{\"datatype\":\"xsd:string\",\"meta\":\"owl:Axiom\",\"object\":\"url:http://en.wikipedia.org/wiki/Alpha_1-antitrypsin_deficiency\"},{\"datatype\":\"xsd:string\",\"meta\":\"owl:Axiom\",\"object\":\"url:http://www.nlm.nih.gov/medlineplus/ency/article/000120.htm\"},{\"datatype\":\"xsd:string\",\"meta\":\"owl:Axiom\",\"object\":\"url:https://alpha1.org/what-is-alpha1/\"},{\"datatype\":\"xsd:string\",\"meta\":\"owl:Axiom\",\"object\":\"url:https://www.genome.gov/Genetic-Disorders/Alpha-1-Antitrypsin-Deficiency\"}]}" } ]