assertion retraction graph subject predicate object datatype annotation 1 0 graph DOID:0081065 IAO:0000115 A diffuse large B-cell lymphoma that is categorized as EZB with high probability by the LymphGen algorithm. This is based on a combination of genetic features and EZB DLBCLs often, but do not always, have hot spot mutations in EZH2 and/or a BCL2 translocation. This class can be further subdivided into two sub-classes EZB-MYC+ and EZB-MYC- using the double hit gene expression signature (DHITsig). This subgroup also commonly has mutations due to aberrant somatic hypermutation affecting IRF8, which can be coding or non-coding. xsd:string "{""oio:hasDbXref"":[{""datatype"":""xsd:string"",""meta"":""owl:Axiom"",""object"":""url:https://pubmed.ncbi.nlm.nih.gov/29641966/""},{""datatype"":""xsd:string"",""meta"":""owl:Axiom"",""object"":""url:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459709/""}]}" 1 0 graph DOID:0081065 rdfs:label EZB diffuse large B-cell lymphoma @en 1 0 graph DOID:0081065 oio:inSubset obo:doid#DO_cancer_slim _IRI 1 0 graph DOID:0081065 oio:id DOID:0081065 xsd:string 1 0 graph DOID:0081065 oio:hasOBONamespace disease_ontology xsd:string 1 0 graph DOID:0081065 oio:hasExactSynonym EZB DLBCL xsd:string 1 0 graph DOID:0081065 oio:hasDbXref NCI:C148398 xsd:string 1 0 graph DOID:0081065 rdfs:subClassOf DOID:0050745 _IRI 1 0 graph DOID:0081065 rdf:type owl:Class _IRI