assertion retraction graph subject predicate object datatype annotation 1 0 graph DOID:0081068 rdfs:label ST2 diffuse large B-cell lymphoma @en 1 0 graph DOID:0081068 oio:inSubset obo:doid#DO_cancer_slim _IRI 1 0 graph DOID:0081068 oio:id DOID:0081068 xsd:string 1 0 graph DOID:0081068 oio:hasOBONamespace disease_ontology xsd:string 1 0 graph DOID:0081068 oio:hasExactSynonym ST2 DLBCL xsd:string 1 0 graph DOID:0081068 rdfs:subClassOf DOID:0050745 _IRI 1 0 graph DOID:0081068 rdf:type owl:Class _IRI 1 0 graph DOID:0081068 IAO:0000115 A diffuse large B-cell lymphoma that is categorized as ST2 with high probability by the LymphGen algorithm. This is based on a combination of genetic features and ST2 DLBCLs often, but do not always, have missense or nonsense mutations affecting TET2 and NFKBIA. This subgroup also commonly has mutations due to aberrant somatic hypermutation affecting some combination of SGK1, ZFP36L1, SOCS1, HIST1H1E and CD83, which can be coding or non-coding. xsd:string "{""oio:hasDbXref"":[{""datatype"":""xsd:string"",""meta"":""owl:Axiom"",""object"":""url:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010183/""},{""datatype"":""xsd:string"",""meta"":""owl:Axiom"",""object"":""url:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459709/""}]}"