ONTIE - Ontology of Immune Epitopes


The Ontology of Immune Epitopes (ONTIE) is an effort to represent terms in the immunology domain in a formal ontology with the specific goal of representing experiments that identify and characterize immune epitopes. It has been developed in conjunction with the Ontology for Biomedical Investigations (OBI) and The Immune Epitope Database and Analysis Resource (IEDB). ONTIE has been developed to be compatible with the OBI ontology as well as other ontologies that are part of the Open Biomedical Ontologies (OBO) Foundry.

ONTIE covers terms regarding immune responses, adaptive immune receptors, immune epitope assays, MHC molecules, and infectious diseases.

ONTIE is (at this development stage) a virtual ontology, drawing together terms from multiple reference ontologies. We are actively working on adding more terms to ONTIE either through term requests or through active contribution to external ontologies.


Formal ontologies are carefully constructed systems of terminology that are designed to help humans and machines search and analyze information, and reason about the world. ONTIE applies formal ontology tools and techniques to immunology. By integrating with existing ontologies in related scientific domains we expand the scope and power of ONTIE.

Related Ontologies

Wherever possible we seek to integrate ONTIE with high-quality scientific ontologies such as these.

Other Resources

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