disease_tree
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DOID:0081064
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label
- BN2 diffuse large B-cell lymphoma @en
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definition
- A diffuse large B-cell lymphoma that is categorized as BN2 with high probability by the LymphGen algorithm. This is based on a combination of genetic features and BN2 DLBCLs often, but do not always, have a translocation involving the BCL6 locus and/or some combination of mutations affecting NOTCH2, TNFAIP3, BCL10 and UBE2A. This subgroup also commonly has mutations due to aberrant somatic hypermutation affecting CD70, which can be coding or non-coding.
xsd:string
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oio:hasDbXref
- url:https://pubmed.ncbi.nlm.nih.gov/29641966/ xsd:string
- url:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459709/ xsd:string
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oio:hasDbXref
- A diffuse large B-cell lymphoma that is categorized as BN2 with high probability by the LymphGen algorithm. This is based on a combination of genetic features and BN2 DLBCLs often, but do not always, have a translocation involving the BCL6 locus and/or some combination of mutations affecting NOTCH2, TNFAIP3, BCL10 and UBE2A. This subgroup also commonly has mutations due to aberrant somatic hypermutation affecting CD70, which can be coding or non-coding.
xsd:string
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has exact synonym
- BN2 DLBCL xsd:string
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has_obo_namespace
- disease_ontology xsd:string
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id
- DOID:0081064 xsd:string
- in_subset
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oio:hasDbXref
- NCI:C148395 xsd:string
- rdf:type
- rdfs:subClassOf