disease_tree
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DOID:0081066
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label
- MCD diffuse large B-cell lymphoma @en
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definition
- A diffuse large B-cell lymphoma that is categorized as MCD with high probability by the LymphGen algorithm. This is based on a combination of genetic features and MCD DLBCLs often, but do not always, have the most common hot spot mutation in MYD88 (L265P) and/or activating mutations in CD79B. This subgroup also commonly has mutations due to aberrant somatic hypermutation affecting PIM1 and/or ETV6, which can be coding or non-coding.
xsd:string
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oio:hasDbXref
- url:https://pubmed.ncbi.nlm.nih.gov/29641966/ xsd:string
- url:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459709/ xsd:string
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oio:hasDbXref
- A diffuse large B-cell lymphoma that is categorized as MCD with high probability by the LymphGen algorithm. This is based on a combination of genetic features and MCD DLBCLs often, but do not always, have the most common hot spot mutation in MYD88 (L265P) and/or activating mutations in CD79B. This subgroup also commonly has mutations due to aberrant somatic hypermutation affecting PIM1 and/or ETV6, which can be coding or non-coding.
xsd:string
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has exact synonym
- MCD DLBCL xsd:string
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has_obo_namespace
- disease_ontology xsd:string
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id
- DOID:0081066 xsd:string
- in_subset
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oio:hasDbXref
- NCI:C148394 xsd:string
- rdf:type
- rdfs:subClassOf